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Some runners develop mushy, white macerated (soft) skin between the toes, which is due to a mixture of bacteria and yeast living in moist toe webs (skin between the toes). In such case, a solution of one part vinegar and 10 parts water should be applied on clean and dry skin for five minutes.
Runners who sweat profusely may get sharply edged but shallow pits on the skin of the sole. This is termed pitting keratolysis and is usually associated with especially foul-smelling feet. The cause of both the pits and the smell is bacteria that love to eat the dead cell layer on the surface of the skin. Treatment consists of measures to reduce sweating by dipping the affected foot in a basin of lukewarm water to which two teabags in a cup of hot water is added.
Frictional forces can cause foot rash, which is due to the shearing forces on the skin by the inner wall of the shoe. The rash on the foot can be prevented by applying petroleum jelly on the feet and by wearing well-fitted running shoes, which are not wet and running socks made of synthetic fibres like polyester, acrylic and nylon, which are designed to wick moisture away from your feet and dry quickly.